A Comparative Study of the Antifungal Activity of Fresh and Dried Solanum anguivi Fruits on Candida albicans and Trichophyton rubrum

In Côte d'Ivoire, as elsewhere in Africa, Solanum anguivi Lam is widely used in traditional medicine to treat bacterial and fungal infections. Given the importance of this plant, the extracts 70%, 80% and 100% from fresh and dried fruits was evaluated for the in vitro growth of two isolates of pathogenic fungi (Candida albicans and Trichophyton rubrum), as well as its anti-free radical activity.

Antifungal tests were carried out by plating 1000 cells of each isolate on Sabouraud agar medium using the double dilution method in inclined tubes. Both extracts were active on the different strains tested, according to a dose-response relationship based on the principle of the method used.

However, extracts from fresh fruit showed good activity on C. albicans, while the dried fresh fruit extracts were highly active on T. rubrum.