miR-221/222 in Tumor and Their Underlying Mechanism

Cao, Xin and Song, Qian and Lu, Xiaoling (2020) miR-221/222 in Tumor and Their Underlying Mechanism. In: Innovations in Medicine and Medical Research Vol. 4. B P International, pp. 30-49. ISBN 978-93-90149-49-0

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Abstract

MicroRNA-221/222 (miRNA-221/222, miR-221/222) is non-coding microRNA which widely distributed
in eukaryotic organisms, and deeply involved in the post-transcriptional regulation of gene
expressions. According to recent studies, abnormal expressions of miR-221/222 are closely related to
the occurrence and development of various kinds of malignant tumors. The role of miR-221/222 in
tumor development and their potential molecular mechanism in various cancers, including liver
cancer, colorectal cancer, cervical cancer, ovarian cancer, and endometrial carcinoma etc, are
summarized and reviewed in this paper. Moreover, the potential translational biomarker role of
abnormal miR-221/222 level in tumor or blood circulation for tumor diagnosis is also discussed.

Item Type: Book Section
Subjects: Research Scholar Guardian > Medical Science
Depositing User: Unnamed user with email support@scholarguardian.com
Date Deposited: 29 Nov 2023 03:48
Last Modified: 29 Nov 2023 03:48
URI: http://science.sdpublishers.org/id/eprint/2049

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