ANTICANCER ACTIVITY OF ZINC OXIDE NANOPARTICLE SYNTHESIS FROM Nelumbo nucifera SEED

The medicinal plants serve as a drug reservoir against a number of diseases. Different methods employed for enhancing their medicinal values and the nanomaterial synthesis is one among them. Those green chemical methods especially used as the promising anti-cancer agents and drug carriers. As a result, the goal of this study was to see how zinc oxide nanoparticles (ZnO-NPs) worked against A549 cells (Human lung cancer cell). In Asia, the seed of the lotus (Nelumbo nucifera) is commonly utilised as a traditional medicine. In this study, N. nucifera dry seed extract was used to make zinc oxide nanoparticles, non-toxic drug carriers. The synthesized well-dispersed and spherical nanoparticles were analysed using scanning electron microscopy, Ultra Violet spectroscopy, Fourier transform infrared, and Scanning Electron Microscope for their characterization. The use of nanoparticles in cancer treatment has gotten a lot of press recently. The Methylthiazolydiphenyl-tetrazolium bromide (MTT) test was used to assess anticancer activity in A549 (Lung Cancer cell). They were treated with ZnO nanoparticles ((ZnO-NPs) they showed a 50% decrease at a low concentration of 31.2 g/ml. These results showed that the anticancer activity of those extract is eventually enhanced by the presence of Zinc oxide Nano particles.