Magnetic Resonance Brain Imaging in Late-Onset Wilson’s Disease: Clinical Features and Review of Literature

Wilson’s disease is a worldwide inherent genetic disorder which leads to copper deposition in various tissues. Recently, Wilson’s disease is classified according to onset of symptoms into early-onset and late-onset Wilson. Magnetic resonance imaging of the brain revealed characteristic bilateral putamena and midbrain tegmental T2 hyperintensity “Face of giant Panda” sign which are reliable imaging features of Wilson’s disease. The objective of this chapter was to review the clinical and magnetic resonance brain imaging changes in late-onset Wilson’s disease.